Yes, graphics settings and programs can have an impact on your PC’s speed. For example, if you are playing a game that is not optimized for your hardware or graphics settings, you could experience slowdowns or lag. As well, certain programs such as video-editing software or 3D modelling software can be quite taxing on your computer’s resources, and can cause slowdowns or lag. In general, if you are using resource-intensive programs, it is best to adjust your graphics and performance settings accordingly in order to optimize your computer’s performance.