There are a few options available to safely clean up the registry on your PC. The best way to clean the registry is to use an automated registry cleaner program, such as CCleaner or Glary Utilities, which will scan your system and clean up any obsolete, broken, or corrupt entries. Another option is to manually clean the registry, but this should only be done by experienced users as incorrect modifications can cause further damage. For a less technical approach, you can download a reputable registry cleaner from the Windows App Store, which will automatically identify and fix any issues with the registry.