1. Supply & Demand: Different cryptocurrencies have different supply and demand, meaning that the amount of units available in circulation vary.
2. Technology: Different cryptocurrencies use different technologies such as PoS (proof-of-stake), PoW (proof-of-work) and other algorithms to secure their networks.
3. Use Cases: Some cryptocurrencies are designed for specific use cases such as peer-to-peer payments or for trading assets on a blockchain.
4. Mining: Cryptocurrencies use different mining techniques such as scrypt, SHA-256 and others.
5. Difficulty: The difficulty of mining and confirming blocks can vary across different cryptocurrencies.
6. Governance: Different cryptocurrencies may be governed differently; some may be open source, while others may be more closed off and privatized.